Departure point: Avenida de América bus station in Madrid
Avenida de América bus station is one of the main bus hubs in Madrid. It connects four metro lines (4, 6, 7, and 9) as well as several urban, intercity, and long-distance bus routes.
Avenida de América bus station is an important transfer hub, connecting the metro with the following bus lines:
- Urban buses in Madrid.
- Intercity buses to towns in the Madrid region: Alcalá de Henares, Móstoles, Getafe, and nearby towns.
- Long-distance buses to other Spanish cities: Salamanca, Barcelona, Valencia, Seville, and others.
Line 223 connects Madrid with Alcalá de Henares. It is one of the fastest and most comfortable options for traveling between the two cities, with an estimated journey time of 30–40 minutes:
- Departs from Avenida de América (Madrid)
- Stops in Canillejas and San Fernando de Henares
- Arrives in Alcalá via Avenida de Madrid and Vía Complutense

Line 223 is a frequent service:
- Weekday buses running more frequently. Especially during rush hours.
- Buses run less often on weekends and holidays. Still fast and comfortable to travel between Madrid and Alcalá de Henares.
Line 223 is a popular choice for traveling between Alcalá de Henares and Madrid. Fast, comfortable, with good connections to Madrid and other cities.
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